The COVID-19 pandemic, an environmental neurology perspective

J. Reis, A. Buguet, G. C. Román, P. S. Spencer

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Neurologists have a particular interest in SARS-CoV-2 because the nervous system is a major participant in COVID-19, both in its acute phase and in its persistent post-COVID phase. The global spread of SARS-CoV-2 infection has revealed most of the challenges and risk factors that humanity will face in the future. We review from an environmental neurology perspective some characteristics that have underpinned the pandemic. We consider the agent, SARS-CoV-2, the spread of SARS-CoV-2 as influenced by environmental factors, its impact on the brain and some containment measures on brain health. Several questions remain, including the differential clinical impact of variants, the impact of SARS-CoV-2 on sleep and wakefulness, and the neurological components of Long-COVID syndrome. We touch on the role of national leaders and public health policies that have underpinned management of the COVID-19 pandemic. Increased awareness, anticipation and preparedness are needed to address comparable future challenges.

Original languageEnglish (US)
Pages (from-to)499-511
Number of pages13
JournalRevue Neurologique
Issue number6
StatePublished - Jun 2022


  • Decision-making
  • Physical-chemical risk
  • Preparedness
  • Social vulnerability
  • Susceptibility
  • Neurology
  • SARS-CoV-2
  • COVID-19/complications
  • Humans
  • Post-Acute COVID-19 Syndrome
  • Pandemics/prevention & control

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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