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The complex dynamics of maxillofacial trauma in blast and fragmentation injuries: Current understanding and gaps in scientific evidence

Ricardo Grillo, Leandro Bottura, Bernardo Correia Lima, Natacha Kalline de Oliveira, Fernando Melhem-Elias, Maria Cristina Zindel Deboni

Research output: Contribution to journalReview articlepeer-review

Abstract

Recent epidemiological data demonstrate a significant rise in blast-induced maxillofacial trauma incidences in both military and civilian settings. This study aimed to comprehensively analyze maxillofacial trauma caused by heavy weaponry, examining blast dynamics, ballistic forces, and fragmentation effects. A comprehensive literature review was conducted using PubMed, SciSpace, and Google Scholar, incorporating studies on blast injuries, ballistic trauma, and war-related maxillofacial damage. Keywords included "maxillofacial injuries", "blast injuries", "ballistic trauma", "high-energy trauma", "heavy weapon injuries", "shock waves", "fragmentation injuries", "missile wounds", "grenade injuries", "shrapnel injuries", and "war-related maxillofacial trauma". Inclusion criteria covered case reports, retrospective analyses, reviews, and clinical trials, while non-human and irrelevant studies were excluded. Data extraction and synthesis were performed to categorize injury mechanisms and surgical challenges. The findings revealed distinct injury patterns, including comminuted fractures, barotrauma-induced sinus ruptures, and thermal-chemical burns. Blast waves preferentially damaged thin bony structures, while high-velocity shrapnel caused widespread soft-tissue disruption. Surgical management is complicated by contamination, delayed necrosis, and polytrauma, necessitating multidisciplinary approaches. Emerging solutions, such as 3D-printed implants and damage-control surgery, show promise but require further validation. Heavy weaponry induces complex maxillofacial trauma that demands tailored, multidisciplinary care. Our review highlights critical gaps in existing protocols and underscores the need for advanced biomaterials, staged reconstruction, and battlefield-adapted surgical strategies. Future research should focus on predictive modeling and standardized guidelines to optimize outcomes in blast-related injuries.

Original languageEnglish (US)
Pages (from-to)1762-1768
Number of pages7
JournalJournal of Cranio-Maxillofacial Surgery
Volume53
Issue number10
DOIs
StatePublished - Oct 2025

Keywords

  • Blast injuries
  • Firearms
  • Forensic ballistics
  • Maxillofacial injury
  • Multiple trauma

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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