The clinical course of patients with septic abortion admitted to an intensive care unit

Javier Finkielman, Fabián Darío De Feo, Paula Graciela Heller, Bekele Afessa

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

Objective: The purpose of this study was to describe the clinical course, complications, and outcome of patients with septic abortion admitted to the intensive care unit (ICU). Design, setting, and patients: In this retrospective study, the records of 63 patients with septic abortion admitted to the ICU of a university hospital in Argentina between 1985 and 1995 were reviewed. Results: The mean age of the patients was 28.5 years, and 33% had had previous abortions. The mean gestational age was 10.5 weeks. The first ICU day Acute Physiology and Chronic Health Evaluation (APACHE) II mean score was 13.9. Acute renal failure developed in 73% (46 of 63) of the patients, disseminated intravascular coagulation (DIC) in 31% (15 of 49), and septic shock in 32% (20 of 63). Blood cultures were positive in 24% (15 of 62). Twelve patients died (19%). Eight of the deaths occurred during the first 48 h of the ICU admission. Compared with survivors, non-survivors had higher median number of organ failures (1.0 vs 4.0, p<0.0001), mean first ICU day SOFA scores (6.6 vs 10.0, p=0.0059), and mean APACHE II scores (12.7 vs 20.2, p=0.0003), and were more likely to have septic shock (18 vs 92%, p<0.0001), and receive dopamine (37 vs 83%, p=0.0040), mechanical ventilation (8 vs 83%, p<0.0001), and pulmonary artery catheter (8 vs 41%, p=0.0026). Conclusions: Although it is an avoidable complication, septic abortion requiring admission to the ICU is associated with high morbidity and mortality.

Original languageEnglish (US)
Pages (from-to)1097-1102
Number of pages6
JournalIntensive Care Medicine
Volume30
Issue number6
DOIs
StatePublished - Jun 1 2004

Keywords

  • APACHE
  • Abortion
  • Female
  • Pregnancy
  • Sepsis
  • Septic abortion

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Fingerprint Dive into the research topics of 'The clinical course of patients with septic abortion admitted to an intensive care unit'. Together they form a unique fingerprint.

Cite this