The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development

P. A. Labosky; G. E. Winnier; H. Sasaki; M. Blessing; B. L.M. Hogan

doi:10.1006/geno.1996.0275

The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development

P. A. Labosky, G. E. Winnier, H. Sasaki, M. Blessing, B. L.M. Hogan

Houston Methodist

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Members of the winged helix family of transcription factors are required for the normal embryonic development of the mouse. Using the interspecific backcross panel from The Jackson Laboratory, we have determined the chromosomal locations of four genes that encode winged helix containing proteins. Mf1 was assigned to mouse Chromosome 8, Mf2 to Chromosome 4, Mf3 to Chromosome 9, and Mf4 to Chromosome 13. Since Mf3 is located in a region of Chromosome 9 containing many well-characterized mouse mutations such as short ear (se), ashen (ash), and dilute (d), we have analyzed deletion mutants to determine the location of Mf3 more precisely.

Original language	English (US)
Pages (from-to)	241-245
Number of pages	5
Journal	Genomics
Volume	34
Issue number	2
DOIs	https://doi.org/10.1006/geno.1996.0275
State	Published - 1996

ASJC Scopus subject areas

Genetics

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10.1006/geno.1996.0275

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abstract = "Members of the winged helix family of transcription factors are required for the normal embryonic development of the mouse. Using the interspecific backcross panel from The Jackson Laboratory, we have determined the chromosomal locations of four genes that encode winged helix containing proteins. Mf1 was assigned to mouse Chromosome 8, Mf2 to Chromosome 4, Mf3 to Chromosome 9, and Mf4 to Chromosome 13. Since Mf3 is located in a region of Chromosome 9 containing many well-characterized mouse mutations such as short ear (se), ashen (ash), and dilute (d), we have analyzed deletion mutants to determine the location of Mf3 more precisely.",

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AB - Members of the winged helix family of transcription factors are required for the normal embryonic development of the mouse. Using the interspecific backcross panel from The Jackson Laboratory, we have determined the chromosomal locations of four genes that encode winged helix containing proteins. Mf1 was assigned to mouse Chromosome 8, Mf2 to Chromosome 4, Mf3 to Chromosome 9, and Mf4 to Chromosome 13. Since Mf3 is located in a region of Chromosome 9 containing many well-characterized mouse mutations such as short ear (se), ashen (ash), and dilute (d), we have analyzed deletion mutants to determine the location of Mf3 more precisely.

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The chromosomal mapping of four genes encoding winged helix proteins expressed early in mouse development

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