The challenge of new daily persistent headache

Randolph W. Evans, Tad D. Seifert

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


New daily persistent headache is a rare chronic daily headache of long duration characterized by the abrupt onset of persistent headache that generally develops over less than 3 days and does not remit. While it was initially thought to be a benign, self-limiting disorder, further research has shown that a significant percentage of patients continue to suffer for many years, often experiencing pain that is refractory to treatment. This article reviews the symptoms, pathophysiology, diagnostic criteria, diagnostic testing, treatment, and prognosis.

Original languageEnglish (US)
Pages (from-to)145-154
Number of pages10
Issue number1
StatePublished - Jan 2011


  • chronic daily headache
  • diagnostic testing
  • new daily persistent headache
  • treatment

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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