The cancer cell-derived extracellular vesicle glycocode in immunoevasion

Jenifer P. Goncalves; Vatsal J. Deliwala; Daniel Kolarich; Fernando Souza-Fonseca-Guimaraes; Joy Wolfram

doi:10.1016/j.it.2022.09.004

The cancer cell-derived extracellular vesicle glycocode in immunoevasion

Jenifer P. Goncalves, Vatsal J. Deliwala, Daniel Kolarich, Fernando Souza-Fonseca-Guimaraes, Joy Wolfram

Houston Methodist

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Recent evidence suggests that cancer cell-derived extracellular vesicles might facilitate immunoevasion. Glycans are known to play a key role in immunomodulation, especially when tethered to biological membranes. However, the extracellular vesicle glycocode in cancer immunoevasion remains a largely unexplored area with promising potential for new putative diagnostic and therapeutic applications.

Original language	English (US)
Pages (from-to)	864-867
Number of pages	4
Journal	Trends in Immunology
Volume	43
Issue number	11
DOIs	https://doi.org/10.1016/j.it.2022.09.004
State	Published - Nov 2022

Keywords

cancer
exosome
extracellular vesicle
glycomics
immunosuppression
microvesicle
Neoplasms/therapy
Humans
Extracellular Vesicles

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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10.1016/j.it.2022.09.004

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title = "The cancer cell-derived extracellular vesicle glycocode in immunoevasion",

abstract = "Recent evidence suggests that cancer cell-derived extracellular vesicles might facilitate immunoevasion. Glycans are known to play a key role in immunomodulation, especially when tethered to biological membranes. However, the extracellular vesicle glycocode in cancer immunoevasion remains a largely unexplored area with promising potential for new putative diagnostic and therapeutic applications.",

keywords = "cancer, exosome, extracellular vesicle, glycomics, immunosuppression, microvesicle, Neoplasms/therapy, Humans, Extracellular Vesicles",

author = "Goncalves, \{Jenifer P.\} and Deliwala, \{Vatsal J.\} and Daniel Kolarich and Fernando Souza-Fonseca-Guimaraes and Joy Wolfram",

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doi = "10.1016/j.it.2022.09.004",

language = "English (US)",

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AU - Goncalves, Jenifer P.

AU - Deliwala, Vatsal J.

AU - Kolarich, Daniel

AU - Souza-Fonseca-Guimaraes, Fernando

AU - Wolfram, Joy

PY - 2022/11

Y1 - 2022/11

N2 - Recent evidence suggests that cancer cell-derived extracellular vesicles might facilitate immunoevasion. Glycans are known to play a key role in immunomodulation, especially when tethered to biological membranes. However, the extracellular vesicle glycocode in cancer immunoevasion remains a largely unexplored area with promising potential for new putative diagnostic and therapeutic applications.

AB - Recent evidence suggests that cancer cell-derived extracellular vesicles might facilitate immunoevasion. Glycans are known to play a key role in immunomodulation, especially when tethered to biological membranes. However, the extracellular vesicle glycocode in cancer immunoevasion remains a largely unexplored area with promising potential for new putative diagnostic and therapeutic applications.

KW - cancer

KW - exosome

KW - extracellular vesicle

KW - glycomics

KW - immunosuppression

KW - microvesicle

KW - Neoplasms/therapy

KW - Humans

KW - Extracellular Vesicles

UR - https://www.scopus.com/pages/publications/85140288423

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M3 - Article

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AN - SCOPUS:85140288423

SN - 1471-4906

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SP - 864

EP - 867

JO - Trends in Immunology

JF - Trends in Immunology

IS - 11

ER -

The cancer cell-derived extracellular vesicle glycocode in immunoevasion

Abstract

Keywords

ASJC Scopus subject areas

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