The cancer cell-derived extracellular vesicle glycocode in immunoevasion

Jenifer P. Goncalves, Vatsal J. Deliwala, Daniel Kolarich, Fernando Souza-Fonseca-Guimaraes, Joy Wolfram

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Recent evidence suggests that cancer cell-derived extracellular vesicles might facilitate immunoevasion. Glycans are known to play a key role in immunomodulation, especially when tethered to biological membranes. However, the extracellular vesicle glycocode in cancer immunoevasion remains a largely unexplored area with promising potential for new putative diagnostic and therapeutic applications.

Original languageEnglish (US)
Pages (from-to)864-867
Number of pages4
JournalTrends in Immunology
Volume43
Issue number11
DOIs
StatePublished - Nov 2022

Keywords

  • cancer
  • exosome
  • extracellular vesicle
  • glycomics
  • immunosuppression
  • microvesicle
  • Neoplasms/therapy
  • Humans
  • Extracellular Vesicles

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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