TY - JOUR
T1 - The 2024 ILTS-ILCA consensus recommendations for liver transplantation for HCC and intrahepatic cholangiocarcinoma
AU - Kodali, Sudha
AU - Kulik, Laura
AU - D'Allessio, Antonio
AU - De Martin, Eleonora
AU - Hakeem, Abdul Rahman
AU - Lewinska, Monica
AU - Lindsey, Stacie
AU - Liu, Ken
AU - Maravic, Zorana
AU - Patel, Madhukar S.
AU - Pinato, David
AU - Rammohan, Ashwin
AU - Rich, Nicole
AU - Sanduzzi Zamparelli, Marco
AU - Victor, David W.
AU - Vinaxia, Carmen
AU - Brombosz, Elizabeth W.
AU - Villanueva, Augusto
AU - Meyer, Tim
AU - Selzner, Nazia
AU - Ghobrial, Rafik Mark
AU - Rela, Mohamed
AU - Sapisochin, Gonzalo
AU - Abdelrahim, Maen
AU - Agopian, Vatche
AU - Balci, Deniz
AU - Bruix, Jordi
AU - Bekaii-Saab, Tanios S.
AU - Berenguer, Marina
AU - Bhangui, Prashant
AU - Bhoori, Sherrie
AU - Chan, Albert Chi Yan
AU - Chan, Stephen L.
AU - Chieh, Alfred Kow Wei
AU - Durand, Francois
AU - Eghtesad, Bijan
AU - Elsabbagh, Ahmed
AU - Halazun, Karim J.
AU - Javle, Milind
AU - Hibi, Taizo
AU - Jung, Dong Hwan
AU - Khalili, Korosh
AU - Lee, Jeong Min
AU - Lewandowski, Robert
AU - Line, Pal Dag
AU - Llovet, Josep Maria
AU - Mazzaferro, Vincenzo
AU - Mas, Valeria
AU - Mehta, Neil
AU - Morement, Helen
AU - O'Kane, Grainne
AU - Paradis, Valerie
AU - Parikh, Neehar
AU - Pillai, Anjana
AU - Polak, Wojtek
AU - Pomposelli, James
AU - Rimassa, Lorenza
AU - Singal, Amit
AU - Soin, Arvinder Singh
AU - Tabrizian, Parissa
AU - Toso, Christian
AU - Valle, Juan
AU - Vibert, Eric
AU - Vogel, Arndt
AU - Rossi, Jessica Zucman
AU - Watt, Kymberly
AU - Woods, Andrea Wilson
N1 - Publisher Copyright:
Copyright © 2025 American Association for the Study of Liver Diseases.
PY - 2025/6/1
Y1 - 2025/6/1
N2 - Liver transplantation (LT) provides the best long-term survival outcomes for patients with liver cancer. As a result, the field of transplant oncology has grown greatly over the past few decades, and many centers have expanded their criteria to allow increased access to LT for liver malignancies. Center-level guidelines and practices in transplant oncology significantly vary across the world, leading to debate regarding the best course of treatment for this patient population. An international consensus conference was convened by the International Liver Transplantation Society and the International Liver Cancer Association on February 1-2, 2024, in Valencia, Spain to establish a more universal consensus regarding LT for oncologic indications. The conference followed the Delphi process, followed by an external expert review. Consensus statements were accepted regarding patient assessment and waitlisting criteria, pretransplant treatment (including immunotherapy) and downstaging, living donor LT, post-LT patient management, and patient-and caregiver-related outcomes. The multidisciplinary participants in the consensus conference provided up-to-date recommendations regarding the selection and management of patients with liver cancer being considered for LT. Although participants deferred to center protocols in many cases, there was great interest in safely expanding access to LT for patients with larger tumor burden and biologically amenable lesions.
AB - Liver transplantation (LT) provides the best long-term survival outcomes for patients with liver cancer. As a result, the field of transplant oncology has grown greatly over the past few decades, and many centers have expanded their criteria to allow increased access to LT for liver malignancies. Center-level guidelines and practices in transplant oncology significantly vary across the world, leading to debate regarding the best course of treatment for this patient population. An international consensus conference was convened by the International Liver Transplantation Society and the International Liver Cancer Association on February 1-2, 2024, in Valencia, Spain to establish a more universal consensus regarding LT for oncologic indications. The conference followed the Delphi process, followed by an external expert review. Consensus statements were accepted regarding patient assessment and waitlisting criteria, pretransplant treatment (including immunotherapy) and downstaging, living donor LT, post-LT patient management, and patient-and caregiver-related outcomes. The multidisciplinary participants in the consensus conference provided up-to-date recommendations regarding the selection and management of patients with liver cancer being considered for LT. Although participants deferred to center protocols in many cases, there was great interest in safely expanding access to LT for patients with larger tumor burden and biologically amenable lesions.
KW - HCC
KW - consensus development conference
KW - intrahepatic cholangiocarcinoma
KW - liver transplantation
KW - transplant oncology
KW - Waiting Lists/mortality
KW - Liver Neoplasms/surgery
KW - Humans
KW - Liver Transplantation/standards
KW - Treatment Outcome
KW - Living Donors
KW - Carcinoma, Hepatocellular/surgery
KW - Bile Duct Neoplasms/surgery
KW - Societies, Medical/standards
KW - Consensus
KW - Patient Selection
KW - Spain
KW - Delphi Technique
KW - Cholangiocarcinoma/surgery
KW - Practice Guidelines as Topic
UR - https://www.scopus.com/pages/publications/86000331526
UR - https://www.scopus.com/inward/citedby.url?scp=86000331526&partnerID=8YFLogxK
U2 - 10.1097/LVT.0000000000000589
DO - 10.1097/LVT.0000000000000589
M3 - Article
C2 - 40014003
AN - SCOPUS:86000331526
SN - 1527-6465
VL - 31
SP - 815
EP - 831
JO - Liver Transplantation
JF - Liver Transplantation
IS - 6
ER -