TGFβ1 regulates HRas-mediated activation of IRE1α through the PERK-RPAP2 axis in keratinocytes

Keyphrases

• Transforming Growth Factor-β 100%
• Keratinocytes 100%
• RNA Polymerase II (RNAPII) 100%
• Associated Proteins 100%
• Inositol-requiring Enzyme 1 (IRE1) 100%
• Protein Kinase R-like Endoplasmic Reticulum Kinase 100%
• 2-axis 100%
• Endoplasmic Reticulum Stress (ER stress) 55%
• Unfolded Protein Response 33%
• Dephosphorylation 22%
• In Vivo Model 11%
• Oncogene 11%
• Tumor Suppression 11%
• Tumor Progression 11%
• Mediated Growth 11%
• Phosphorylation 11%
• Kinase Cascade 11%
• Senescence 11%
• Mutant Forms 11%
• Disease Model 11%
• Growth Arrest 11%
• Genetic Approach 11%
• Phosphatase 11%
• Pharmacological Approaches 11%
• Tumor Suppressive Role 11%
• Sensor Protein 11%
• Adaptative Response 11%

Biochemistry, Genetics and Molecular Biology

• Enzyme 100%
• Keratinocyte 100%
• Fibrinogen 100%
• Phosphotransferase 100%
• Kinase 100%
• RNA Polymerase II 100%
• Cancer Growth Factor 100%
• Inositol 100%
• Endoplasmic Reticulum Stress 55%
• Unfolded Protein Response 33%
• Carcinogenesis 22%
• Dephosphorylation 22%
• Oncogene 11%
• Tumor Progression 11%
• Genetic Approach 11%
• Phosphatase 11%

Immunology and Microbiology

• Endoplasmic Reticulum 100%
• Cancer Growth Factor 100%
• Fibrinogen 100%
• Keratinocyte 100%
• RNA Polymerase 100%
• Endoplasmic Reticulum Stress 55%
• Unfolded Protein Response 33%
• Dephosphorylation 22%
• Oncogene 11%
• In Vitro 11%
• Phosphatase 11%