Textile for heart valve prostheses: Fabric long-term durability testing

Frederic Heim, Bernard Durand, Nabil Chakfe

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

The rapid developments and success in percutaneous vascular surgery over the last two decades with the now common stent grafts implantation, make the noninvasive surgery technique today attractive even for heart valve replacement. Less traumatic for the patient and also less time consuming, percutaneous heart valve replacement is however at its beginning and restricted to end of life patients. The noninvasive procedure expects from the heart valve prosthesis material to be resistant and adapted to folding requirements of the implantation process (catheter). Polyester fabric could be a suited material for heart valve implanted percutaneously. Highly flexible and resistant, polyester fabric proved to be well adapted to the dynamic behavior of a valve and polyester (Dacron) is also widely used for vascular grafts implantation and shows good biocompatibility and durability. However, today there's no data available on long-term durability of fabric used as heart valve material. The purpose of this work is to study the long term behavior of a microdenier polyester fabric construction under combined in vitro flexure and tension fatigue stress. In the novel in vitro testing technique presented, a fabric specimen was subjected to combined flexural and tensile fatigue generated by fluid flow under physiological pressure conditions. The results obtained show how flexural properties change with fatigue time, which reflects directly on the suitability of a fabric in such devices. It was also observed that these fabric structural changes directly influence the in vitro behavior of the textile heart valve prosthesis.

Original languageEnglish (US)
Pages (from-to)68-77
Number of pages10
JournalJournal of Biomedical Materials Research - Part B Applied Biomaterials
Volume92
Issue number1
DOIs
StatePublished - Jan 2010

Keywords

  • Fatigue testing
  • Heart valve
  • In vitro
  • Prosthesis
  • Vascular

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering

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