Testicular tumors: Clinically relevant histological findings

A. G. Ayala, J. Y. Ro

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Testicular germ cell neoplasms affect young man in the prime of life. Although the overwhelming majority are malignant, they are curable. In addition to the stage of the disease and the presence of serum markers, there are important pathological changes that have clinical significance. These include (1) the cell type, (2) the amount of the component, and (3) the presence or absence of vascular invasion. Pure embryonal carcinoma or embryonal carcinoma in excess of 80% in a mixed tumor and vascular/lymphatic invasion are high-risk factors as they are predictors of relapse. These factors should be recognized by the pathologist and should be taken into account by the oncologist when selecting the management of a patient with a germ cell tumor of the testis.

Original languageEnglish (US)
Pages (from-to)72-81
Number of pages10
JournalSeminars in Urologic Oncology
Issue number2
StatePublished - 1998


  • Embryonal carcinoma
  • Germ cell tumor
  • Nonseminomatous germ cell tumor
  • Prognostic factors
  • Seminoma
  • Vascular invasion

ASJC Scopus subject areas

  • Urology


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