Tendon and ligament engineering

Nicholas Sears, Tyler Touchet, Hugh Benhardt, Elizabeth Cosgriff-Hernández

Research output: Chapter in Book/Report/Conference proceedingChapter


Overall, musculoskeletal ailments comprise more than 14% of health care expenditures in the United States. Ligament and tendon damage account for a signicant portion of these ailments with over 32 million traumatic and repetitive motion injuries reported in the United States each year. Although numerous tendon injuries can be surgically repaired, large gaps and missing tendons require a gra or replacement device. Among the most common tendon injuries are traumatic and attritional tears of the rotator cu, resulting in 4.4 million physician visits and over 50,000 repair surgeries performed each year (Praemer et al. 1999; Butler et al. 2008). However, tendons repaired in this manner are oen weak and susceptible to reinjury. Excessive muscle contraction and neurovascular damage following surgical repair of rotator cu injuries result in failure rates as high as 40%. Tendon injuries can dramatically aect a patient’s quality of life; however, improving functional outcomes aer tendon injury remains a signicant clinical challenge.

Original languageEnglish (US)
Title of host publicationTissue Engineering
Subtitle of host publicationPrinciples and Practices
PublisherCRC Press
ISBN (Electronic)9781439874035
ISBN (Print)9781439874004
StatePublished - Jan 1 2012

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Engineering(all)
  • Materials Science(all)


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