Temporary Percutaneous Mechanical Circulatory Support in Advanced Heart Failure

Jessica L. Brown, Jerry D. Estep

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Cardiogenic shock is severe, refractory heart failure caused by significant myocardial dysfunction in the setting of adequate preload that is accompanied by systemic hypoperfusion. Progressive end-organ dysfunction is a hallmark of persistent cardiogenic shock and necessitates intervention to overcome altered hemodynamics and restore end-organ perfusion. Temporary percutaneous mechanical circulatory support is an established modality in the treatment of cardiogenic shock and is increasingly used in patients with cardiogenic shock as a bridge to recovery or further definitive therapy. This article reviews the current devices, their effects on left ventricular hemodynamics, and the evidence supporting their continued use.

Original languageEnglish (US)
Pages (from-to)385-398
Number of pages14
JournalHeart Failure Clinics
Issue number3
StatePublished - Jul 1 2016


  • Cardiogenic shock
  • ECMO
  • IABP
  • Impella
  • Percutaneous mechanical circulatory support
  • Pressure-volume loop
  • TandemHeart

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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