Temporal fluctuations in proton relaxation times

Dirk Sostman; Sami Zoghbi; John Gore

doi:10.1016/0730-725X(86)90026-3

Temporal fluctuations in proton relaxation times

Dirk Sostman, Sami Zoghbi, John Gore

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We studied mouse liver, heart and kidney for possible diurnal fluctuations of T₁ and T₂. In a subgroup of animals, we attempted to relate T₁ and T₂ of the organ samples to their water and lipid content (and in the liver, also to glycogen content). Diurnal periodic fluctuation was found only in liver T₂ and was of a very minor degree. Regression analysis of organ T₂ estabilished relationships with chemical composition which explained 25%-40% of the observed variation in T₂. No relationship with T₁ could be established.

Original language	English (US)
Pages (from-to)	479-483
Number of pages	5
Journal	Magnetic Resonance Imaging
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/0730-725X(86)90026-3
State	Published - 1986

Keywords

Circadian rhythms
Proton relaxation

ASJC Scopus subject areas

Condensed Matter Physics
Radiology Nuclear Medicine and imaging
Structural Biology
Clinical Biochemistry
Biophysics

Access to Document

10.1016/0730-725X(86)90026-3

Cite this

@article{8599c122234543f1bd8ad025a18d4c0a,

title = "Temporal fluctuations in proton relaxation times",

abstract = "We studied mouse liver, heart and kidney for possible diurnal fluctuations of T1 and T2. In a subgroup of animals, we attempted to relate T1 and T2 of the organ samples to their water and lipid content (and in the liver, also to glycogen content). Diurnal periodic fluctuation was found only in liver T2 and was of a very minor degree. Regression analysis of organ T2 estabilished relationships with chemical composition which explained 25%-40% of the observed variation in T2. No relationship with T1 could be established.",

keywords = "Circadian rhythms, Proton relaxation",

author = "Dirk Sostman and Sami Zoghbi and John Gore",

note = "Funding Information: Acknorcledg~~~enf-One of the authors (J.G.) was supported by PHS Grant No. 1 ROI CA40675-01, awarded by the National Cancer Institute. DHHS. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1986",

doi = "10.1016/0730-725X(86)90026-3",

language = "English (US)",

volume = "4",

pages = "479--483",

journal = "Magnetic Resonance Imaging",

issn = "0730-725X",

publisher = "Elsevier",

number = "6",

}

TY - JOUR

T1 - Temporal fluctuations in proton relaxation times

AU - Sostman, Dirk

AU - Zoghbi, Sami

AU - Gore, John

N1 - Funding Information: Acknorcledg~~~enf-One of the authors (J.G.) was supported by PHS Grant No. 1 ROI CA40675-01, awarded by the National Cancer Institute. DHHS. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1986

Y1 - 1986

N2 - We studied mouse liver, heart and kidney for possible diurnal fluctuations of T1 and T2. In a subgroup of animals, we attempted to relate T1 and T2 of the organ samples to their water and lipid content (and in the liver, also to glycogen content). Diurnal periodic fluctuation was found only in liver T2 and was of a very minor degree. Regression analysis of organ T2 estabilished relationships with chemical composition which explained 25%-40% of the observed variation in T2. No relationship with T1 could be established.

AB - We studied mouse liver, heart and kidney for possible diurnal fluctuations of T1 and T2. In a subgroup of animals, we attempted to relate T1 and T2 of the organ samples to their water and lipid content (and in the liver, also to glycogen content). Diurnal periodic fluctuation was found only in liver T2 and was of a very minor degree. Regression analysis of organ T2 estabilished relationships with chemical composition which explained 25%-40% of the observed variation in T2. No relationship with T1 could be established.

KW - Circadian rhythms

KW - Proton relaxation

UR - http://www.scopus.com/inward/record.url?scp=0022885909&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022885909&partnerID=8YFLogxK

U2 - 10.1016/0730-725X(86)90026-3

DO - 10.1016/0730-725X(86)90026-3

M3 - Article

AN - SCOPUS:0022885909

SN - 0730-725X

VL - 4

SP - 479

EP - 483

JO - Magnetic Resonance Imaging

JF - Magnetic Resonance Imaging

IS - 6

ER -

Temporal fluctuations in proton relaxation times

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this