Temporal fluctuations in proton relaxation times

Dirk Sostman, Sami Zoghbi, John Gore

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We studied mouse liver, heart and kidney for possible diurnal fluctuations of T1 and T2. In a subgroup of animals, we attempted to relate T1 and T2 of the organ samples to their water and lipid content (and in the liver, also to glycogen content). Diurnal periodic fluctuation was found only in liver T2 and was of a very minor degree. Regression analysis of organ T2 estabilished relationships with chemical composition which explained 25%-40% of the observed variation in T2. No relationship with T1 could be established.

Original languageEnglish (US)
Pages (from-to)479-483
Number of pages5
JournalMagnetic Resonance Imaging
Volume4
Issue number6
DOIs
StatePublished - 1986

Keywords

  • Circadian rhythms
  • Proton relaxation

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Radiology Nuclear Medicine and imaging
  • Structural Biology
  • Clinical Biochemistry
  • Biophysics

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