9 Scopus citations

Abstract

Cellular senescence of endothelial cells plays an important role in the development of vascular lesions that ultimately lead to an atherosclerotic plaque. This review focuses on the age-related changes of endothelial and vascular smooth muscle cells that contribute to vascular disease and discusses potential new targets that could rejuvenate the vascular system and thereby prevent or delay atherosclerosis.

Original languageEnglish (US)
Pages (from-to)172-175
Number of pages4
JournalMethodist DeBakey cardiovascular journal
Volume11
Issue number3
DOIs
StatePublished - Jul 1 2015

Keywords

  • aging
  • atherosclerosis
  • cellular senescence
  • endothelium
  • modified MRNA
  • prevention
  • telomerase

ASJC Scopus subject areas

  • Medicine(all)

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