Systems and methods for improving cerebrospinal fluid (csf) drainage

Eugene V. Golanov (Inventor), Gavin W. Britz (Inventor), Angelique Regnier-Golanov (Inventor), Christof Karmonik (Inventor), Alan Eskuri (Inventor)

Research output: Patent

Abstract

Systems and methods for draining cerebrospinal fluid (CSF) are described herein described herein. In one implementation, an example system includes a signal generator, a plurality of electrodes operably connected to the signal generator, and a controller operably connected to the signal generator. The controller includes a processor and a memory. The controller is configured to deliver a neuromuscular electrical stimulation signal including at least one burst of pulses to at least one muscle in the subject's neck. The neuromuscular electrical stimulation signal is configured to induce a plurality of contractions of the at least one muscle. Additionally, the contractions of the at least one muscle are configured to squeeze at least one lymph node to create a pumping force, and the pumping force is configured to direct CSF flow in a proximal direction. The results in CSF drainage through the subject's neck lymphatic system.
Original languageEnglish (US)
Patent numberWO2022226155A1
Filing date4/21/22
StatePublished - Oct 27 2022

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