Abstract
The Rauwolfia alkaloids reserpine (1) and deserpidine (2), two alkaloids from Rauwolfia species, have been widely used for their antihypertensive action. Deserpidine (2) is a compound with limited availability from natural sources, and its synthesis from 1 in six steps (41% overall yield) is reported here.
Original language | English (US) |
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Pages (from-to) | 1629-1631 |
Number of pages | 3 |
Journal | Journal of Natural Products |
Volume | 68 |
Issue number | 11 |
DOIs | |
State | Published - Nov 1 2005 |
ASJC Scopus subject areas
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry