Synthesis and antibacterial activity of 3-(5-methylisoxazol-3-yl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives

Xin Ping Hui; Peng Fei Xu; Qin Wang; Qi Zhang; Zi Yi Zhang

doi:10.1002/cjoc.20010191015

Synthesis and antibacterial activity of 3-(5-methylisoxazol-3-yl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives

Xin Ping Hui, Peng Fei Xu, Qin Wang, Qi Zhang, Zi Yi Zhang

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The condensed products 2-10 of 4-amino-5-mercapto-3-(5-methylisoxazol-3-yl)-1,2,4-triazole (1) with chloroacetaldehyde, 2-bromocyclohexanone, chloranil, ω-bromo-ω-(1H-1, 2,4-triazol-1-yl)acetophenone, 2-bromo-4′-substituted acetophenones and 2-bromo-6′-methoxy-2′-acetonaphthone were described. Hie antibacterial activities were also evaluated.

Original language	English (US)
Pages (from-to)	991-995
Number of pages	5
Journal	Chinese Journal of Chemistry
Volume	19
Issue number	10
DOIs	https://doi.org/10.1002/cjoc.20010191015
State	Published - 2001

Keywords

1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazine
5-methylisoxazole
Antibacterial activity

ASJC Scopus subject areas

Chemistry(all)

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10.1002/cjoc.20010191015

Cite this

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title = "Synthesis and antibacterial activity of 3-(5-methylisoxazol-3-yl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives",

abstract = "The condensed products 2-10 of 4-amino-5-mercapto-3-(5-methylisoxazol-3-yl)-1,2,4-triazole (1) with chloroacetaldehyde, 2-bromocyclohexanone, chloranil, ω-bromo-ω-(1H-1, 2,4-triazol-1-yl)acetophenone, 2-bromo-4′-substituted acetophenones and 2-bromo-6′-methoxy-2′-acetonaphthone were described. Hie antibacterial activities were also evaluated.",

keywords = "1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazine, 5-methylisoxazole, Antibacterial activity",

author = "Hui, {Xin Ping} and Xu, {Peng Fei} and Qin Wang and Qi Zhang and Zhang, {Zi Yi}",

year = "2001",

doi = "10.1002/cjoc.20010191015",

language = "English (US)",

volume = "19",

pages = "991--995",

journal = "Chinese Journal of Chemistry",

issn = "1001-604X",

publisher = "Shanghai Institute of Organic Chemistry",

number = "10",

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TY - JOUR

T1 - Synthesis and antibacterial activity of 3-(5-methylisoxazol-3-yl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives

AU - Hui, Xin Ping

AU - Xu, Peng Fei

AU - Wang, Qin

AU - Zhang, Qi

AU - Zhang, Zi Yi

PY - 2001

Y1 - 2001

N2 - The condensed products 2-10 of 4-amino-5-mercapto-3-(5-methylisoxazol-3-yl)-1,2,4-triazole (1) with chloroacetaldehyde, 2-bromocyclohexanone, chloranil, ω-bromo-ω-(1H-1, 2,4-triazol-1-yl)acetophenone, 2-bromo-4′-substituted acetophenones and 2-bromo-6′-methoxy-2′-acetonaphthone were described. Hie antibacterial activities were also evaluated.

AB - The condensed products 2-10 of 4-amino-5-mercapto-3-(5-methylisoxazol-3-yl)-1,2,4-triazole (1) with chloroacetaldehyde, 2-bromocyclohexanone, chloranil, ω-bromo-ω-(1H-1, 2,4-triazol-1-yl)acetophenone, 2-bromo-4′-substituted acetophenones and 2-bromo-6′-methoxy-2′-acetonaphthone were described. Hie antibacterial activities were also evaluated.

KW - 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazine

KW - 5-methylisoxazole

KW - Antibacterial activity

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DO - 10.1002/cjoc.20010191015

M3 - Article

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VL - 19

SP - 991

EP - 995

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

SN - 1001-604X

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Synthesis and antibacterial activity of 3-(5-methylisoxazol-3-yl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine derivatives

Abstract

Keywords

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