Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma

Mari Kogiso, Lin Qi, Yuchen Du, Frank K. Braun, Huiyuan Zhang, L. Frank Huang, Lei Guo, Yulun Huang, Wan Yee Teo, Holly Lindsay, Sibo Zhao, Sarah G. Injac, Zhen Liu, Vidya Mehta, Diep Tran, Feng Li, Patricia A. Baxter, Jack M. Su, Laszlo Perlaky, D. Williams ParsonsMurali Chintagumpala, Adekunle Adesina, Yongcheng Song, Xiao Nan Li

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Medicine & Life Sciences