TY - JOUR
T1 - Surgical treatment of mitral regurgitation
AU - Lawrie, Gerald M.
N1 - Funding Information:
The study was funded by The Houston Methodist Hospital Foundation through the Michael E. DeBakey Distinguished Chair of Cardiac Surgery which was funded through the generosity of The Robert Allison Family.
Publisher Copyright:
Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2020/9
Y1 - 2020/9
N2 - Purpose of review Mitral repair is the best treatment for degenerative mitral regurgitation. Many patients are referred too late for optimal outcomes. The US repair vs. replacement rate is only 60-80%, at a time when the inferiority of replacement has been established. Therefore, widely used traditional techniques of repair are being reappraised. Recent findings Identification of risk factors predictive of poor early and late outcome have improved timing for surgical referral. Composite risk scores have been developed. Novel echocardiographic, cardiac MRI, and molecular level risk factors could improve timing. Analysis of factors contributing to low repair rates is also of critical importance. The role of institutional and surgeon volumes have been identified. More detailed data on the importance of dynamic function of the mitral valve have led to improved repair techniques such as intraoperative simulation of end diastole and early systole, use of expanded polytetrafluoroethylene neochords instead of leaflet resection, and dynamic instead of rigid annuloplasty. Summary Our perception of mitral regurgitation has changed from a seemingly simple condition to one of considerable complexity at multiple levels. National guidelines should be studied and followed.
AB - Purpose of review Mitral repair is the best treatment for degenerative mitral regurgitation. Many patients are referred too late for optimal outcomes. The US repair vs. replacement rate is only 60-80%, at a time when the inferiority of replacement has been established. Therefore, widely used traditional techniques of repair are being reappraised. Recent findings Identification of risk factors predictive of poor early and late outcome have improved timing for surgical referral. Composite risk scores have been developed. Novel echocardiographic, cardiac MRI, and molecular level risk factors could improve timing. Analysis of factors contributing to low repair rates is also of critical importance. The role of institutional and surgeon volumes have been identified. More detailed data on the importance of dynamic function of the mitral valve have led to improved repair techniques such as intraoperative simulation of end diastole and early systole, use of expanded polytetrafluoroethylene neochords instead of leaflet resection, and dynamic instead of rigid annuloplasty. Summary Our perception of mitral regurgitation has changed from a seemingly simple condition to one of considerable complexity at multiple levels. National guidelines should be studied and followed.
KW - Mitral regurgitation diagnosis
KW - Mitral regurgitation referral timing
KW - Mitral valve surgical repair
UR - http://www.scopus.com/inward/record.url?scp=85089302083&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85089302083&partnerID=8YFLogxK
U2 - 10.1097/HCO.0000000000000772
DO - 10.1097/HCO.0000000000000772
M3 - Review article
C2 - 32740446
AN - SCOPUS:85089302083
SN - 0268-4705
VL - 35
SP - 491
EP - 499
JO - Current Opinion in Cardiology
JF - Current Opinion in Cardiology
IS - 5
ER -