Surface modification and patterning of biomolecules and cells, using a polymer lift-off template

Christine P. Tan, Jose M. Moran-Mirabal, Daniel J. Brooks, B. Rob Ilic, Claudia Fischbach-Teschl, Harold G. Craighead

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

There is a growing interest in patterning biomolecules and cells on modified surfaces, as they enable the direct study of biological entities with their environment. We demonstrate the fabrication and use of a polymer (Parylene C) lift-off template, to pattern a variety of biological materials and cells, with feature sizes ranging from micrometers to a minimum width of 300 nm. Our goal is to create highly reproducible arrays, for studying biomolecule-cell and cell-cell interactions.

Original languageEnglish
Title of host publication12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference
PublisherChemical and Biological Microsystems Society
Pages1552-1554
Number of pages3
StatePublished - Jan 1 2008
Event12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States
Duration: Oct 12 2008Oct 16 2008

Other

Other12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
CountryUnited States
CitySan Diego, CA
Period10/12/0810/16/08

Keywords

  • Cell culture
  • Parylene
  • Patterning
  • Surface modification

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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