We have reported a general method for biocompatible modification and multi-functionalization of semiconductor quantum dots (QDs) through direct reaction of organic silanes on the surface of semiconductor QDs. Functionalized QDs, including CdSe/ZnS, CdSe/CdS core/shell and PbS QDs, have been prepared at high concentration up to 10-4 M in homogeneous media, i.e. toluene. Fluorescence spectra and TEM images indicate that the modified QDs exhibit strong fluorescence and single particle features, respectively. Fluorescence images show that biocompatible CdSe/ZnS QDs are internalized into SK-BR-3 breast cancer cells after hydrophilic modification. Additionally, methacrylate- modified QDs have been used as monomers for radical polymerization.
|Original language||English (US)|
|Number of pages||6|
|Journal||Journal of Materials Chemistry|
|State||Published - 2007|
ASJC Scopus subject areas
- Materials Chemistry