Abstract
Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene "peel-off" stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensors and biological microenvironments. A variety of substituted precursors enables direct coating of functionalised parylenes onto biomedical implants and microfluidics, providing a convenient method for designing biocompatible and bioactive surfaces. This article will review the emerging role and applications of parylene as a biomaterial for surface chemical modification and provide a future outlook.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1803-1832 |
| Number of pages | 30 |
| Journal | Materials |
| Volume | 3 |
| Issue number | 3 |
| DOIs | |
| State | Published - 2010 |
Keywords
- [2.2]paracyclophane
- Bioactive
- Biomaterial
- Biomolecular
- Microarray
- Microfluidic
- Micropatterning
- Nanobiotechnology
- Parylene
- Surface modification
ASJC Scopus subject areas
- General Materials Science