Supraorbital Nerve and Cavernous Sinus Invasion with Poorly Differentiated Carcinoma of Unknown Primary

Saagar N. Patel, Mohammad Obadah Nakawah, Ama Sadaka, Shauna Berry, Juan Ortiz Gomez, Suzanne Powell, Andrew G. Lee

Research output: Contribution to journalArticle

Abstract

A 50-year-old man presented with a 4-month history of right-sided trigeminal neuropathy in the V1 and V2 distribution, right sixth nerve palsy and Horner syndrome. Magnetic resonance imaging (MRI) showed enhancement and thickening along the right ophthalmic nerve and supraorbital nerve and fullness at the right cavernous sinus extending to Meckel’s cave. Evaluation for a primary tumour was negative. Cavernous sinus biopsy showed infiltrating poorly differentiated carcinoma; the patient underwent radiation therapy. To our knowledge this is the only case of poorly differentiated carcinoma involving the supraorbital nerve presenting with trigeminal neuropathy and Horner syndrome in the English ophthalmic literature.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalNeuro-Ophthalmology
Volume42
Issue number5
DOIs
StateAccepted/In press - Jan 11 2018

Keywords

  • Carcinoma
  • cavernous sinus
  • perineural invasion
  • supraorbital nerve

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology

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