Superselective Intra-arterial Chemotherapy of Advanced Paranasal Sinus Tumors

Ya Yen Lee, Isaiah W. Dimery, Pamela Van Tassel, Charles De Pena, J. Bob Blacklock, Helmuth Goepfert

Research output: Contribution to journalArticlepeer-review

82 Scopus citations


Twenty-four patients with advanced paranasal sinus tumors were treated with combined superselective intra-arterial and systemic chemotherapy, yielding an immediate satisfactory tumor response rate of 91%, significantly better than previously reported. Eight patients had craniofacial surgery circumvented because of complete or near complete response. Repetitive uncomplicated catheterization of the pterygoid segment of the internal maxillary artery using a coaxial system is the cornerstone of successful induction chemotherapy. Strenuous screening of medical status is mandatory for this aggressive introduction chemotherapy.

Original languageEnglish (US)
Pages (from-to)503-511
Number of pages9
JournalArchives of Otolaryngology--Head and Neck Surgery
Issue number4
StatePublished - Apr 1989

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


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