Sudden death in a 15-year-old with diffuse cardiac rhabdomyomatosis: An autopsy case report

Maren Y. Fuller, Dwayne Wolf, L. Maximilian Buja

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A 15-year-old African-American female with a 4-month history of sporadic rapid heartbeat and fatigue was found pulseless and apneic in her residence. At autopsy, patchy scarring was diffuse throughout the circumference of the left ventricle of the heart. Microscopically, the myocardium had diffuse infiltration of rhabdomyoma-like cells with significant associated fibrosis. Unlike cardiac rhabdomyoma, there was no discrete tumor mass. Differential diagnoses considered were congenital cardiac rhabdomyoma with partial regression, cardiac fibroma, histiocytoid cardiomyopathy, glycogen storage diseases, and drug-induced vacuolar cardiomyopathy. However, the findings are most consistent with cardiac rhabdomyomatosis, an entity not well described in the literature.

Original languageEnglish (US)
Pages (from-to)351-353
Number of pages3
JournalCardiovascular Pathology
Volume23
Issue number6
DOIs
StatePublished - Nov 1 2014

Keywords

  • Cardiac rhabdomyomatosis
  • Sudden cardiac death

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pathology and Forensic Medicine

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