Sudden death caused by bradycardia and asystole in a heart transplant patient with coronary arteriopathy

W. C. Grinstead, F. W. Smart, Craig Pratt, D. G. Weilbaecher, M. E. Sekela, G. P. Noon, J. B. Young

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

The mechanism of death as a result of allograft ischemic heart disease is not well characterized. Ventricular tachycardia and fibrillation may not be the terminal events they often are in the general population. We report observations in a 41-year-old man with cardiac allograft arteriopathy who died suddenly while wearing an ambulatory monitor. The lethal rhythm was a progressive bradycardia terminating in asystole. Autopsy revealed epicardial and small vessel intramyocardial, coronary arteriopathy, and only mild allograft rejection. It is our belief that ischemia caused the bradycardic sudden death. We would like to hypothesize that prophylactic permanent pacemaker implantation may prevent bradycardic sudden death and improve survival in heart transplant patients with coronary disease.

Original languageEnglish (US)
Pages (from-to)931-936
Number of pages6
JournalJournal of Heart and Lung Transplantation
Volume10
Issue number6
StatePublished - Dec 1 1991

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Transplantation

Fingerprint Dive into the research topics of 'Sudden death caused by bradycardia and asystole in a heart transplant patient with coronary arteriopathy'. Together they form a unique fingerprint.

Cite this