@article{da66429eaeac45fbae898d11d5c2e43f,
title = "Successful treatment of bloodstream infection due to metallo-β-lactamase-producing Stenotrophomonas maltophilia in a renal transplant patient",
abstract = "Stenotrophomonas maltophilia is an emerging multidrug-resistant (MDR) opportunistic pathogen for which new antibiotic options are urgently needed. We report our clinical experience treating a 19-year-old renal transplant recipient who developed prolonged bacteremia due to metallo-β-lactamase-producing S. maltophilia refractory to conventional treatment. The infection recurred despite a prolonged course of colistimethate sodium (colistin) but resolved with the use of a novel drug combination with clinical efficacy against the patient's S. maltophilia isolate.",
author = "Mojica, {Maria F.} and Ouellette, {Christopher P.} and Amy Leber and Becknell, {M. Brian} and Ardura, {Monica I.} and Federico Perez and Masako Shimamura and Bonomo, {Robert A.} and Aitken, {Samuel L.} and Shelburne, {Samuel A.}",
note = "Funding Information: Research described in this case report was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under awards R01AI100560, R01AI072219, and R01AI063517 to R.A.B. Additionally, F.P. is supported through UL1TR000439 from the National Center for Advancing Translational Sciences (NCATS) component of the National Institutes of Health and NIH Roadmap for Medical Research. The content of this case report is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. This case report was supported in part by funds and/or facilities provided by the Cleveland Department of Veterans Affairs to R.A.B. and Veterans Affairs Merit Review Program award 1I01BX001974 from the U.S. Department of Veterans Affairs Biomedical Laboratory Research and Development Service to R.A.B. This work was supported in part by funds provided by the Geriatric Research Education and Clinical Center VISN 10 to R.A.B. and F.P. The contents do not represent the views of the U.S. Department of Veterans Affairs or the U.S. Government. This work, including the efforts of Robert A. Bonomo, was funded by Veterans Affairs Research and Development. This work, including the efforts of Robert A. Bonomo, was funded by HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) (R01AI100560, R01AI072219, and R01AI063517). This work, including the efforts of Federico Perez, was funded by HHS | NIH | National Center for Advancing Translational Sciences (NCATS) (UL1TR000439). Publisher Copyright: Copyright {\textcopyright} 2016, American Society for Microbiology. All Rights Reserved.",
year = "2016",
month = sep,
day = "1",
doi = "10.1128/AAC.00264-16",
language = "English (US)",
volume = "60",
pages = "5130--5134",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "9",
}