Successful ceftriaxone therapy of endocarditis due to penicillin non-susceptible viridans streptococci

Samuel Shelburne; Stephen B. Greenberg; Saima Aslam; David J. Tweardy

doi:10.1016/j.jinf.2006.05.010

Successful ceftriaxone therapy of endocarditis due to penicillin non-susceptible viridans streptococci

Samuel Shelburne, Stephen B. Greenberg, Saima Aslam, David J. Tweardy

Research Institute

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14 Scopus citations

Abstract

Viridans streptococci are a major cause of infective endocarditis, and penicillin non-susceptibility is increasing in these organisms. We present the initial reported case of infective endocarditis due to penicillin non-susceptible viridans streptococci successfully treated with ceftriaxone monotherapy. The lack of evidence supporting the recommendations for treatment of endocarditis due to penicillin non-susceptible viridans streptococci is discussed.

Original language	English (US)
Pages (from-to)	e99-e101
Journal	Journal of Infection
Volume	54
Issue number	2
DOIs	https://doi.org/10.1016/j.jinf.2006.05.010
State	Published - Feb 2007

Keywords

Antibacterial drug resistance
Bacterial endocarditis
Ceftriaxone
Viridans streptococci

ASJC Scopus subject areas

Applied Microbiology and Biotechnology
Microbiology
Parasitology
Virology
Immunology and Allergy
Infectious Diseases

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10.1016/j.jinf.2006.05.010

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title = "Successful ceftriaxone therapy of endocarditis due to penicillin non-susceptible viridans streptococci",

abstract = "Viridans streptococci are a major cause of infective endocarditis, and penicillin non-susceptibility is increasing in these organisms. We present the initial reported case of infective endocarditis due to penicillin non-susceptible viridans streptococci successfully treated with ceftriaxone monotherapy. The lack of evidence supporting the recommendations for treatment of endocarditis due to penicillin non-susceptible viridans streptococci is discussed.",

keywords = "Antibacterial drug resistance, Bacterial endocarditis, Ceftriaxone, Viridans streptococci",

author = "Samuel Shelburne and Greenberg, {Stephen B.} and Saima Aslam and Tweardy, {David J.}",

note = "Funding Information: The authors thank Charles Stager, Ph.D. for performance of the serum bactericidal assay. This work was supported in part by National Institutes of Health grant K12-RR17665 (to S.A.S.). Copyright: Copyright 2008 Elsevier B.V., All rights reserved.",

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language = "English (US)",

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AU - Shelburne, Samuel

AU - Greenberg, Stephen B.

AU - Aslam, Saima

AU - Tweardy, David J.

N1 - Funding Information: The authors thank Charles Stager, Ph.D. for performance of the serum bactericidal assay. This work was supported in part by National Institutes of Health grant K12-RR17665 (to S.A.S.). Copyright: Copyright 2008 Elsevier B.V., All rights reserved.

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N2 - Viridans streptococci are a major cause of infective endocarditis, and penicillin non-susceptibility is increasing in these organisms. We present the initial reported case of infective endocarditis due to penicillin non-susceptible viridans streptococci successfully treated with ceftriaxone monotherapy. The lack of evidence supporting the recommendations for treatment of endocarditis due to penicillin non-susceptible viridans streptococci is discussed.

AB - Viridans streptococci are a major cause of infective endocarditis, and penicillin non-susceptibility is increasing in these organisms. We present the initial reported case of infective endocarditis due to penicillin non-susceptible viridans streptococci successfully treated with ceftriaxone monotherapy. The lack of evidence supporting the recommendations for treatment of endocarditis due to penicillin non-susceptible viridans streptococci is discussed.

KW - Antibacterial drug resistance

KW - Bacterial endocarditis

KW - Ceftriaxone

KW - Viridans streptococci

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Successful ceftriaxone therapy of endocarditis due to penicillin non-susceptible viridans streptococci

Abstract

Keywords

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