Subpopulations of T cells in lung biopsies from patients with pigeon breeder's disease

Roberto Barrios, Moisés Selman, Ramón Franco, Rocio Chapela, J. Sullivan López, Teresa I. Fortoul

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Monoclonal antibodies were used to determine surface phenotypes of T cells in tissue obtained by open lung biopsies from patients with chronic hypersensitivity pneumonitis (pigeon breeder's disease). The results indicate that an increased number of suppressor/cytotoxic cells is present in these patients when compared with the number of helper/inducer cells. These findings, which were present within the interstitium, are consistent with those found in bronchoalveolar lavage of patients with this disease. In addition, in two-thirds of the patients there was a greater total number of helper and suppressor cells than the total count for Pan T cells. A possible interpretation of these findings might be the presence of both markers in the same cell.

Original languageEnglish (US)
Pages (from-to)181-187
Number of pages7
JournalLung
Volume165
Issue number1
DOIs
StatePublished - Dec 1987

Keywords

  • Alveolitis allergic
  • Immunopathology
  • Lung disease, Interstitial
  • Pigeon breeder's disease
  • Pneumonitis, hypersensitivity
  • T-Cell subpopulations

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Physiology

Fingerprint Dive into the research topics of 'Subpopulations of T cells in lung biopsies from patients with pigeon breeder's disease'. Together they form a unique fingerprint.

Cite this