Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

C. Bissardon; O. Proux; S. Bureau; E. Suess; L. H.E. Winkel; R. S. Conlan; L. W. Francis; I. M. Khan; L. Charlet; J. L. Hazemann; S. Bohic

doi:10.1039/c9an00207c

Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

C. Bissardon, O. Proux, S. Bureau, E. Suess, L. H.E. Winkel, R. S. Conlan, L. W. Francis, I. M. Khan, L. Charlet, J. L. Hazemann, S. Bohic

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (μg kg^-1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.

Original language	English (US)
Pages (from-to)	3488-3493
Number of pages	6
Journal	Analyst
Volume	144
Issue number	11
DOIs	https://doi.org/10.1039/c9an00207c
State	Published - Jun 7 2019

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Environmental Chemistry
Spectroscopy
Electrochemistry

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title = "Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage",

abstract = "The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (μg kg-1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.",

author = "C. Bissardon and O. Proux and S. Bureau and E. Suess and Winkel, {L. H.E.} and Conlan, {R. S.} and Francis, {L. W.} and Khan, {I. M.} and L. Charlet and Hazemann, {J. L.} and S. Bohic",

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doi = "10.1039/c9an00207c",

language = "English (US)",

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T1 - Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

AU - Bissardon, C.

AU - Proux, O.

AU - Bureau, S.

AU - Suess, E.

AU - Winkel, L. H.E.

AU - Conlan, R. S.

AU - Francis, L. W.

AU - Khan, I. M.

AU - Charlet, L.

AU - Hazemann, J. L.

AU - Bohic, S.

PY - 2019/6/7

Y1 - 2019/6/7

N2 - The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (μg kg-1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.

AB - The speciation of highly-diluted elements by X-ray absorption spectroscopy in a diverse range of materials is extremely challenging, especially in biological matrices such as articular cartilage. Here we show that using a high energy resolution fluorescence detected X-ray absorption spectroscopy (HERFD-XAS) technique coupled to an array of crystal analyzers, selenium speciation down to 400 ppb (μg kg-1) within articular cartilage can be demonstrated. This is a major advance in the speciation of highly-diluted elements through X-ray absorption spectroscopy and opens new possibilities to study the metabolic role of selenium and other elements in biological samples.

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Sub-ppm level high energy resolution fluorescence detected X-ray absorption spectroscopy of selenium in articular cartilage

Abstract

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