Studies on the Metabolism of Steroids in the Foetus: Biosynthesis of 3‐Hydroxy‐Δ4‐C19 Steroids in the Human Foetal Liver

Belisário P. Lisboa, Jan‐Åke Gustafsson

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

After incubation of testosterone with the 105000 ×g microsome fraction from human foetal liver 4‐androstene‐3α,17β‐diol was isolated. Incubation of testosterone with the 105000 ×g supernatant fraction resulted in the formation of 4‐androstene‐3α(and 3β),17β‐diol. When incubated with liver slices testosterone was metabolized into 4‐androstene‐3α,17β‐diol and 3α‐ and 3β‐hydroxy‐4‐androsten‐17‐one.

Original languageEnglish (US)
Pages (from-to)556-559
Number of pages4
JournalEuropean Journal of Biochemistry
Volume14
Issue number3
DOIs
StatePublished - Jul 1970

ASJC Scopus subject areas

  • Biochemistry

Fingerprint Dive into the research topics of 'Studies on the Metabolism of Steroids in the Foetus: Biosynthesis of 3‐Hydroxy‐Δ<sup>4</sup>‐C<sub>19</sub> Steroids in the Human Foetal Liver'. Together they form a unique fingerprint.

Cite this