TY - JOUR
T1 - Studies on the Metabolism of Steroids in the Foetus
T2 - Biosynthesis of 3‐Hydroxy‐Δ4‐C19 Steroids in the Human Foetal Liver
AU - Lisboa, Belisário P.
AU - Gustafsson, Jan‐Åke
N1 - Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1970/7
Y1 - 1970/7
N2 - After incubation of testosterone with the 105000 ×g microsome fraction from human foetal liver 4‐androstene‐3α,17β‐diol was isolated. Incubation of testosterone with the 105000 ×g supernatant fraction resulted in the formation of 4‐androstene‐3α(and 3β),17β‐diol. When incubated with liver slices testosterone was metabolized into 4‐androstene‐3α,17β‐diol and 3α‐ and 3β‐hydroxy‐4‐androsten‐17‐one.
AB - After incubation of testosterone with the 105000 ×g microsome fraction from human foetal liver 4‐androstene‐3α,17β‐diol was isolated. Incubation of testosterone with the 105000 ×g supernatant fraction resulted in the formation of 4‐androstene‐3α(and 3β),17β‐diol. When incubated with liver slices testosterone was metabolized into 4‐androstene‐3α,17β‐diol and 3α‐ and 3β‐hydroxy‐4‐androsten‐17‐one.
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U2 - 10.1111/j.1432-1033.1970.tb00323.x
DO - 10.1111/j.1432-1033.1970.tb00323.x
M3 - Article
C2 - 5479382
AN - SCOPUS:0014813935
SN - 0014-2956
VL - 14
SP - 556
EP - 559
JO - European Journal of Biochemistry
JF - European Journal of Biochemistry
IS - 3
ER -