Studies on the Metabolism of C21 Steroids in Rat Liver: Hydroxylation of Progesterone in Rat Liver Microsomes

Jan‐Åke Gustafsson, Belisário P. Lisboa

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Progesterone was incubated with 105000 ×g liver microsome preparations from adult male rats and the hydroxylated 3‐oxo‐δ4‐steroids formed were isolated and identified by thin‐layer chromatography and gas chromatography‐mass spectrometry. The following compounds were characterized: 2α‐, 6β‐, 6α‐, 7α‐, 15α‐, 15β‐ and 16α‐hydroxyprogesterone.

Original languageEnglish (US)
Pages (from-to)525-530
Number of pages6
JournalEuropean Journal of Biochemistry
Volume15
Issue number3
DOIs
StatePublished - Sep 1970

ASJC Scopus subject areas

  • Biochemistry

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