Structure and specific DNA binding of the rat liver glucocorticoid receptor

Jan Åke Gustafsson, Jan Carlstedt-Duke, Sam Okret, Ann Charlotte Wikström, Örjan Wrange, Farhang Payvar, Keith Yamamoto

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

During recent years major advances have been made in our understanding of glucocorticoid mechanism of action. This progress has been made possible by access to purified glucocorticoid receptor in significant amounts as well as by application of hybrid DNA technology within the field of glucocorticoid control of gene expression. Especially the mammary tumour virus genome has turned out to be a convenient experimental system suitable for such investigations. This paper summarizes some of the work carried out in our own laboratory, partially in collaboration with Dr Keith Yamamoto and his associates at the Department of Biochemistry and Biophysics, University of California, San Francisco, U.S.A.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalJournal of Steroid Biochemistry
Volume20
Issue number1
DOIs
StatePublished - Jan 1984

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology

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