Structural and metabolic requirements for activators of the peroxisome proliferator-activated receptor

Medicine & Life Sciences

• Peroxisome Proliferator-Activated Receptors 100%
• Fatty Acids 62%
• 1-(carboxyethylthio)tetradecane 20%
• Unsaturated Fatty Acids 19%
• Esters 18%
• 1-(carboxymethylthio)tetradecane 17%
• pirinixic acid 15%
• DNA receptor 14%
• Ligands 12%
• Acyl Coenzyme A 12%
• Coenzyme A 11%
• Cyclooxygenase Inhibitors 11%
• Glucocorticoid Receptors 10%
• Reporter Genes 9%
• Cytochrome P-450 Enzyme System 8%
• Signal Transduction 7%
• In Vitro Techniques 4%

Chemistry

• Metabolic 67%
• Fatty Acid 66%
• P450 Inhibitor 19%
• EC 1.14.99.1 (Prostaglandin-Endoperoxide Synthase) Inhibitor 17%
• Glucocorticoid 15%
• Acyl-CoA 15%
• Ester 14%
• Saturated Fatty Acid 14%
• Polyunsaturated Fatty Acid 13%
• Unsaturated Fatty Acid 13%
• Radical Scavenger 13%
• Signal Transduction 12%
• Cytochrome P450 12%
• Pharmacological Metabolism 9%
• Metabolite 8%
• Acid 8%
• Ligand 5%
• Molecule 4%