TY - JOUR
T1 - Strontium doped calcium phosphate coatings on poly(etheretherketone) (PEEK) by pulsed electron deposition
AU - Bianchi, Michele
AU - Degli Esposti, Lorenzo
AU - Ballardini, Alberto
AU - Liscio, Fabiola
AU - Berni, Matteo
AU - Gambardella, Alessandro
AU - Leeuwenburgh, Sander C.G.
AU - Sprio, Simone
AU - Tampieri, Anna
AU - Iafisco, Michele
N1 - Publisher Copyright:
© 2017 Elsevier B.V.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2017/6/15
Y1 - 2017/6/15
N2 - Herein the preparation of Sr2 +-doped calcium phosphate (CaP) coatings on poly(etheretherketone) (PEEK) substrates by pulsed electron deposition (PED) was investigated. Hydroxyapatites (HA) substituted with tailored amounts of Sr2 + up to 9 wt% were synthesized to generate the deposition targets. Dense and uniform amorphous CaP films having Sr/Ca molar ratios close to that of targets were achieved. The roughness and the wettability of the bare PEEK were significantly enhanced after coating deposition. The presence of Sr2 + led to a slight increase of the particles size while it did not mainly affect the RMS of the coatings that consisted of nanostructured aggregates of globular shape. After a mild annealing treatment at 130 °C for 6 h, the amorphous coatings transformed into nanocrystalline HA films incorporating Sr2 + having Sr/Ca molar ratios close to those of the as-deposited films. The annealing did not affect the topography and the roughness of the coatings, while improved the hardness of the films un-doped and doped at low-extent. This study shows that PED is feasible technique to coat PEEK implants with CaP films with control over the Sr/Ca ratio, which could improve bone fixation and in vivo stability especially under osteoporotic conditions thanks to the anabolic effect of Sr2 +.
AB - Herein the preparation of Sr2 +-doped calcium phosphate (CaP) coatings on poly(etheretherketone) (PEEK) substrates by pulsed electron deposition (PED) was investigated. Hydroxyapatites (HA) substituted with tailored amounts of Sr2 + up to 9 wt% were synthesized to generate the deposition targets. Dense and uniform amorphous CaP films having Sr/Ca molar ratios close to that of targets were achieved. The roughness and the wettability of the bare PEEK were significantly enhanced after coating deposition. The presence of Sr2 + led to a slight increase of the particles size while it did not mainly affect the RMS of the coatings that consisted of nanostructured aggregates of globular shape. After a mild annealing treatment at 130 °C for 6 h, the amorphous coatings transformed into nanocrystalline HA films incorporating Sr2 + having Sr/Ca molar ratios close to those of the as-deposited films. The annealing did not affect the topography and the roughness of the coatings, while improved the hardness of the films un-doped and doped at low-extent. This study shows that PED is feasible technique to coat PEEK implants with CaP films with control over the Sr/Ca ratio, which could improve bone fixation and in vivo stability especially under osteoporotic conditions thanks to the anabolic effect of Sr2 +.
KW - Calcium phosphate
KW - Hydroxyapatite
KW - Osteoporosis
KW - Poly(etheretherketone)
KW - Pulsed electron deposition
KW - Strontium
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U2 - 10.1016/j.surfcoat.2017.04.012
DO - 10.1016/j.surfcoat.2017.04.012
M3 - Article
AN - SCOPUS:85017439391
VL - 319
SP - 191
EP - 199
JO - Surface and Coatings Technology
JF - Surface and Coatings Technology
SN - 0257-8972
ER -