Stroke-related restless legs syndrome: epidemiology, clinical characteristics, and pathophysiology

Xi Xi Wang, Ya Feng, Eng King Tan, William G. Ondo, Yun Cheng Wu

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Stroke-related restless legs syndrome (RLS) is one of stroke-related sleep disorders, which may be due to de novo RLS after stroke onset or an exacerbation of RLS symptoms after incident stroke. To date, the diagnostic rate of stroke-related RLS is low but it has a significant effect on patients' daily life and functional outcome. This review provides an overview of the epidemiology, clinical characteristics, pathophysiology, and impact on functional outcome of stroke-related RLS.

Original languageEnglish (US)
Pages (from-to)238-248
Number of pages11
JournalSleep Medicine
StatePublished - Feb 2022


  • Anatomical considerations
  • Prevalence
  • Restless legs syndrome
  • Stroke
  • Stroke/complications
  • Humans
  • Restless Legs Syndrome
  • Sleep Wake Disorders/epidemiology

ASJC Scopus subject areas

  • Medicine(all)


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