@inproceedings{a69002492c5a451899a42c3ff37055de,
title = "Strain-based parameters for infarct localization: Evaluation via a learning algorithm on a synthetic database of pathological hearts",
abstract = "Localization of infarcted regions is essential to determine the most appropriate treatment for patients with cardiac ischemia. Myocardial strain partially reflects the location of infarcted regions, which demonstrated potential use in clinical practice. However, strain patterns are complex and simple thresholding is not sufficient to locate the infarcts. Besides, many strain-based parameters exist and their sensitivities to myocardial infarcts have not been directly investigated. In our study, we propose to evaluate nine strain-based parameters to locate infarcted regions. For this purpose, we designed a large database (n = 200) of synthetic pathological finite-element heart models from 5 real healthy left ventricle geometries. The infarcts were incorporated with random location, shape and degree of severity. In addition, we used a state-of-the-art learning algorithm to link deformation patterns and infarct location. Based on our evaluation, we propose to sort the strain-based parameters into three groups according to their performances in locating infarcts.",
keywords = "Finite-element model, Infarct diagnosis, Machine learning, Myocardial infarct, Myocardial strain",
author = "Rumindo, {Gerardo Kenny} and Nicolas Duchateau and Pierre Croisille and Jacques Ohayon and Patrick Clarysse",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing AG 2017.; 9th International Conference on Functional Imaging and Modelling of the Heart, FIMH 2017 ; Conference date: 11-06-2017 Through 13-06-2017",
year = "2017",
doi = "10.1007/978-3-319-59448-4_11",
language = "English (US)",
isbn = "9783319594477",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer-Verlag",
pages = "106--114",
editor = "Mihaela Pop and Wright, {Graham A.}",
booktitle = "Functional Imaging and Modelling of the Heart - 9th International Conference, FIMH 2017, Proceedings",
}