Abstract
The evolution of biology into a large-scale quantitative molecular science has been paralleled by concomitant advances in computer storage systems, processing power, and data-analysis algorithms. The application of computer technologies to molecular biology data has given rise to a new system-based approach to biological research. Bioinformatics addresses problems related to the storage, retrieval and analysis of information about biological structure, sequence and function. Its goals include the development of integrated storage systems and analysis tools to interpret molecular biology data in a biologically meaningful manner in normal and disease processes and in efforts for drag discovery. This paper reviews recent developments in data management, storage, and retrieval that are central to the effective use of structural and functional genomics in fulfilling these goals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 248-263 |
| Number of pages | 16 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 4676 |
| DOIs | |
| State | Published - 2002 |
Keywords
- Analysis
- Bioinformatics
- Computational biology
- Data management
- Database
- Functional genomics
- Retrieval
- Storage
- Structural genomics
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering