Storage, data management and retrieval in bioinformatics

Stephen T. Wong, Anil Patwardhan

Research output: Contribution to journalArticle

Abstract

The evolution of biology into a large-scale quantitative molecular science has been paralleled by concomitant advances in computer storage systems, processing power, and data-analysis algorithms. The application of computer technologies to molecular biology data has given rise to a new system-based approach to biological research. Bioinformatics addresses problems related to the storage, retrieval and analysis of information about biological structure, sequence and function. Its goals include the development of integrated storage systems and analysis tools to interpret molecular biology data in a biologically meaningful manner in normal and disease processes and in efforts for drag discovery. This paper reviews recent developments in data management, storage, and retrieval that are central to the effective use of structural and functional genomics in fulfilling these goals.

Original languageEnglish (US)
Pages (from-to)248-263
Number of pages16
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume4676
DOIs
StatePublished - Jan 1 2002

Keywords

  • Analysis
  • Bioinformatics
  • Computational biology
  • Data management
  • Database
  • Functional genomics
  • Retrieval
  • Storage
  • Structural genomics

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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