Steroids in primates: 5-androstene-3β, 16α, 17β-triol excretion by a pregnant irus monkey (macaca pascicularis)

M. E. Manson; C. H.L. Shackleton; F. L. Mitchell; J. Å Gustafsson; J. Sjovall

doi:10.1016/S0039-128X(71)80170-8

Steroids in primates: 5-androstene-3β, 16α, 17β-triol excretion by a pregnant irus monkey (macaca pascicularis)

M. E. Manson, C. H.L. Shackleton, F. L. Mitchell, J. Å Gustafsson, J. Sjovall

Houston Methodist

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The major compound present in the steroid monosulfate fraction of urine from a macaque monkey (Macaca fascicularis) during pregnancy was identified by gas chromatography-mass spectrometry as 5-androstene-3β, 16α, 17β-triol. The excretion of this compound increased throughout the period of gestation (from 10 to 130 μg/24 hr). Other compounds identified were 3β-hydroxy-5-androsten-17-one, 5-androstene-3β, 17β-diol and three androstane-3, 16, 17-triols.

Original language	English (US)
Pages (from-to)	51-57
Number of pages	7
Journal	Steroids
Volume	18
Issue number	1
DOIs	https://doi.org/10.1016/S0039-128X(71)80170-8
State	Published - Jul 1971

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Endocrinology
Pharmacology
Clinical Biochemistry
Organic Chemistry

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10.1016/S0039-128X(71)80170-8

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@article{0a4cad98393a4f0f922cd8636b5525cf,

title = "Steroids in primates: 5-androstene-3β, 16α, 17β-triol excretion by a pregnant irus monkey (macaca pascicularis)",

abstract = "The major compound present in the steroid monosulfate fraction of urine from a macaque monkey (Macaca fascicularis) during pregnancy was identified by gas chromatography-mass spectrometry as 5-androstene-3β, 16α, 17β-triol. The excretion of this compound increased throughout the period of gestation (from 10 to 130 μg/24 hr). Other compounds identified were 3β-hydroxy-5-androsten-17-one, 5-androstene-3β, 17β-diol and three androstane-3, 16, 17-triols.",

author = "Manson, \{M. E.\} and Shackleton, \{C. H.L.\} and Mitchell, \{F. L.\} and Gustafsson, \{J. {\AA}\} and J. Sjovall",

note = "Funding Information: We wish to thank Dr. C. Coid and Mr. P. Dawson for supplying the urine samples and Mr. J. Hancock for technical assistance. Part of the study was financed by the Swedish Medical Research Council (grant No. 13X-219). J.-\textasciitilde{}. G. is indebted to {"}Syskonen Wessen Stiftelse{"} for a fellowship. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",

year = "1971",

month = jul,

doi = "10.1016/S0039-128X(71)80170-8",

language = "English (US)",

volume = "18",

pages = "51--57",

journal = "Steroids",

issn = "0039-128X",

publisher = "Elsevier",

number = "1",

}

TY - JOUR

T1 - Steroids in primates

T2 - 5-androstene-3β, 16α, 17β-triol excretion by a pregnant irus monkey (macaca pascicularis)

AU - Manson, M. E.

AU - Shackleton, C. H.L.

AU - Mitchell, F. L.

AU - Gustafsson, J. Å

AU - Sjovall, J.

N1 - Funding Information: We wish to thank Dr. C. Coid and Mr. P. Dawson for supplying the urine samples and Mr. J. Hancock for technical assistance. Part of the study was financed by the Swedish Medical Research Council (grant No. 13X-219). J.-~. G. is indebted to "Syskonen Wessen Stiftelse" for a fellowship. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.

PY - 1971/7

Y1 - 1971/7

N2 - The major compound present in the steroid monosulfate fraction of urine from a macaque monkey (Macaca fascicularis) during pregnancy was identified by gas chromatography-mass spectrometry as 5-androstene-3β, 16α, 17β-triol. The excretion of this compound increased throughout the period of gestation (from 10 to 130 μg/24 hr). Other compounds identified were 3β-hydroxy-5-androsten-17-one, 5-androstene-3β, 17β-diol and three androstane-3, 16, 17-triols.

AB - The major compound present in the steroid monosulfate fraction of urine from a macaque monkey (Macaca fascicularis) during pregnancy was identified by gas chromatography-mass spectrometry as 5-androstene-3β, 16α, 17β-triol. The excretion of this compound increased throughout the period of gestation (from 10 to 130 μg/24 hr). Other compounds identified were 3β-hydroxy-5-androsten-17-one, 5-androstene-3β, 17β-diol and three androstane-3, 16, 17-triols.

UR - https://www.scopus.com/pages/publications/0015089469

UR - https://www.scopus.com/inward/citedby.url?scp=0015089469&partnerID=8YFLogxK

U2 - 10.1016/S0039-128X(71)80170-8

DO - 10.1016/S0039-128X(71)80170-8

M3 - Article

C2 - 4999738

AN - SCOPUS:0015089469

SN - 0039-128X

VL - 18

SP - 51

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JO - Steroids

JF - Steroids

IS - 1

ER -

Steroids in primates: 5-androstene-3β, 16α, 17β-triol excretion by a pregnant irus monkey (macaca pascicularis)

Abstract

ASJC Scopus subject areas

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