Steroid receptors in benign prostatic hyperplasia (BPH) and prostatic cancer

Encouraged by the promising possibilities of predicting the sensitivity of a mammary tumor to hormonal treatment offered by measurement of its content of steroid receptors, the author carried out similar studies with benign prostatic cancer. The presence of a specific androgen receptor was demonstrated in both BPH and carcinomatous tissue. A specific receptor for progestins was also discovered, while no receptors for estrogens or glucocorticoids were detected in BPH tissue.