TY - JOUR
T1 - Status of study on biological and toxicological effects of nanoscale materials
AU - Wang, Bing
AU - Feng, Weiyue
AU - Zhao, Yuliang
AU - Xing, Gengmei
AU - Chai, Zhifang
AU - Wang, Haifang
AU - Jia, Guang
N1 - Funding Information:
Acknowledgements The authors thank Prof. Liu Yuanfang of Peking University for the valuable discussion. This work was supported by the National Natural Science Foundation of China (Grant No. 10490180), the Ministry of Science and Technology of China (Grant No. 2001CCA03800) and the Chinese Academy of Sciences and National Center for Nanoscience and Nanotechnology and Institute of High Energy Physics.
Funding Information:
Recently, at a workshop cosponsored by the National Natural Science Foundation of China and the US Environmental Protection Agency, scientists urged to firstly solve the following critical issues for the risk assessment of manufactured nanoparticles or nanoma-terials[22]: (i) Toxicology of manufactured nanoparticles; (ii) exposure assessment system of manufactured nanoparticles; (iii) the possibility to extrapolate manufactured nano-particle toxicity using the existing particle and fiber toxicological databases; (iv) the trans- portation, persistence and transformation of manufactured nanoparticles in environmental and biological system; (v) the recyclability and overall sustainability of manufactured nanoparticles in the ecological system.
PY - 2005/10
Y1 - 2005/10
N2 - Because the physical and chemical properties of nanosized materials mostly differ from the existing microsized materials, their potential impacts on human health and the environment will be topics under the serious discussions in press and in a number of international scientific journals. We analyze and summarize the existing data of the experimental study on the biological activities and adverse effects of nanoscale materials/particles including single wall carbon nanotubes, multi wall carbon nanotubes, titanium oxide and iron powders. Though some biological behaviors of nanoscale materials observed cannot be understood on the basis of the current knowledge, as the existing data are mostly preliminary, it is too early to make some exclusive conclusions on biological activities (or the toxicity) of any of nanoscale materials. The experimental techniques, the current topics, and the future research directions for this new research field are also discussed.
AB - Because the physical and chemical properties of nanosized materials mostly differ from the existing microsized materials, their potential impacts on human health and the environment will be topics under the serious discussions in press and in a number of international scientific journals. We analyze and summarize the existing data of the experimental study on the biological activities and adverse effects of nanoscale materials/particles including single wall carbon nanotubes, multi wall carbon nanotubes, titanium oxide and iron powders. Though some biological behaviors of nanoscale materials observed cannot be understood on the basis of the current knowledge, as the existing data are mostly preliminary, it is too early to make some exclusive conclusions on biological activities (or the toxicity) of any of nanoscale materials. The experimental techniques, the current topics, and the future research directions for this new research field are also discussed.
KW - Biological activity and toxicological effect
KW - Multi wall carbon nanotubes
KW - Nanomaterials
KW - Single wall carbon nanotubes
KW - Titanium oxide and iron
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U2 - 10.1360/042004-26
DO - 10.1360/042004-26
M3 - Article
AN - SCOPUS:27944466230
SN - 1006-9291
VL - 48
SP - 385
EP - 394
JO - Science in China, Series B: Chemistry
JF - Science in China, Series B: Chemistry
IS - 5
ER -