Keyphrases
DNA Damage
100%
Phosphorylation
100%
Cisplatin
100%
Human Cancer
100%
P21Cip1
100%
Cancer Model
100%
Platinum-based
100%
P53 Phosphorylation
100%
CDDP
85%
1,2-Diaminocyclohexane
71%
Murine Double Minute 2 (MDM2)
57%
Phosphoinositide 3-kinase (PI3K)
42%
Resistant Cells
42%
Transactivation
42%
Tumor
28%
Dose Effect
28%
Wild-type p53
28%
Western Blot Analysis
14%
Cancer Cell Lines
14%
P53 Protein
14%
Phosphorylation State
14%
Cytotoxic Effect
14%
P53 Gene
14%
Cyclin-dependent Kinase Inhibitor
14%
Platinum Agents
14%
Wortmannin
14%
Cross-resistance
14%
Platinum Analogs
14%
Cisplatin Resistance
14%
Chemorefractory
14%
Biochemistry, Genetics and Molecular Biology
P53
100%
Cancer Model
100%
Cisplatin
57%
Mdm2
28%
Transactivation
21%
Wild Type
14%
DNA Damage
14%
Western Blot
7%
Cancer Cell
7%
P21
7%
Cytotoxicity
7%
Phosphotransferase
7%
Kinase
7%
Cyclin-Dependent Kinase
7%
Phosphoinositide 3-Kinase
7%
Protein P53
7%
Cross Resistance
7%
Neuroscience
P53
100%
Cancer Model
100%
Cisplatin
53%
Transactivation
20%
DNA Damage
13%
Cell Line
6%
Cytotoxicity
6%
Western Blot
6%
Kinase
6%
Phosphoinositide 3-Kinase
6%
Wortmannin
6%
Cyclin-Dependent Kinase
6%
Pharmacology, Toxicology and Pharmaceutical Science
Protein P53
100%
Cancer Model
100%
Cisplatin
53%
Malignant Neoplasm
6%
Phosphotransferase
6%
Western Blot
6%
Cytotoxicity
6%
Antiinfective Agent
6%
Phosphatidylinositol 3 Kinase
6%
Cyclin Dependent Kinase Inhibitor
6%
Platinum Derivative
6%
Wortmannin
6%
Cross-Resistance
6%