TY - JOUR
T1 - Staphylococcus aureus
T2 - A Community Pathogen
AU - Miller, Loren G.
AU - Kaplan, Sheldon L.
N1 - Copyright:
Copyright 2009 Elsevier B.V., All rights reserved.
PY - 2009/3
Y1 - 2009/3
N2 - Staphylococcus aureus is a common human pathogen. S aureus infections most commonly clinically manifest as skin infections. There has been much interest in S aureus infections in the community over the past decade because of the rise of community-associated methicillin-resistant S aureus (CA-MRSA) infections, which have emerged globally over a relatively short period of time. In contrast to health care-associated methicillin resistant S aureus (HA-MRSA), circulating strains of CA-MRSA have characteristic pathogenesis, strain characteristics, epidemiology, and clinical manifestations that are distinct from HA-MRSA. In fact, CA-MRSA probably behaves more like community-associated methicillin-sensitive S aureus (MSSA). This article reviews current knowledge of the epidemiology and clinical manifestations of community-associated S aureus and CA-MRSA infections.
AB - Staphylococcus aureus is a common human pathogen. S aureus infections most commonly clinically manifest as skin infections. There has been much interest in S aureus infections in the community over the past decade because of the rise of community-associated methicillin-resistant S aureus (CA-MRSA) infections, which have emerged globally over a relatively short period of time. In contrast to health care-associated methicillin resistant S aureus (HA-MRSA), circulating strains of CA-MRSA have characteristic pathogenesis, strain characteristics, epidemiology, and clinical manifestations that are distinct from HA-MRSA. In fact, CA-MRSA probably behaves more like community-associated methicillin-sensitive S aureus (MSSA). This article reviews current knowledge of the epidemiology and clinical manifestations of community-associated S aureus and CA-MRSA infections.
KW - Clinical syndromes
KW - Community infections
KW - Epidemiology
KW - Methicillin-resistance
KW - MRSA
KW - Staphylococcus aureus
UR - http://www.scopus.com/inward/record.url?scp=58149180098&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=58149180098&partnerID=8YFLogxK
U2 - 10.1016/j.idc.2008.10.002
DO - 10.1016/j.idc.2008.10.002
M3 - Review article
C2 - 19135915
AN - SCOPUS:58149180098
SN - 0891-5520
VL - 23
SP - 35
EP - 52
JO - Infectious Disease Clinics of North America
JF - Infectious Disease Clinics of North America
IS - 1
ER -