Staphylococcus aureus: A Community Pathogen

Loren G. Miller, Sheldon Kaplan

Research output: Contribution to journalReview article

92 Scopus citations

Abstract

Staphylococcus aureus is a common human pathogen. S aureus infections most commonly clinically manifest as skin infections. There has been much interest in S aureus infections in the community over the past decade because of the rise of community-associated methicillin-resistant S aureus (CA-MRSA) infections, which have emerged globally over a relatively short period of time. In contrast to health care-associated methicillin resistant S aureus (HA-MRSA), circulating strains of CA-MRSA have characteristic pathogenesis, strain characteristics, epidemiology, and clinical manifestations that are distinct from HA-MRSA. In fact, CA-MRSA probably behaves more like community-associated methicillin-sensitive S aureus (MSSA). This article reviews current knowledge of the epidemiology and clinical manifestations of community-associated S aureus and CA-MRSA infections.

Original languageEnglish (US)
Pages (from-to)35-52
Number of pages18
JournalInfectious Disease Clinics of North America
Volume23
Issue number1
DOIs
StatePublished - Mar 1 2009

Keywords

  • Clinical syndromes
  • Community infections
  • Epidemiology
  • Methicillin-resistance
  • MRSA
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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