Staphylococcal adhesion to collagen in intpa-articular sepsis

Anna Voytek, Anthony G. Gristana, Elin Barth, Quentin Myrvik, Lech Switalski, Magnus Hook, Pietro Speziale

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Ultrastructural studies of the cartilaginous articular surfaces of human and rabbit joints have shown that cartilage is the target substratum for adhesion by Staphylococcus aureus, leading to intra-articular sepsis. Transmission and scanning electron microscope studies demonstrated bacteria in intimate contact with acellular cartilage matrix surfaces, particularly with collagen fibres. Certain strains of Staphylococcus aureus used in these experiments reveal a high binding capacity to collagen that is derived from a cartilage matrix. These studies indicate that the pathogenesis of intra-articular sepsis is based on the ability of certain strains of staphylococci to bind preferentially to a cartilage matrix.

Original languageEnglish (US)
Pages (from-to)107-110
Number of pages4
Issue number1
StatePublished - Jan 1988


  • collagen
  • Intra-articular sepsis
  • microbial adhesion
  • Staphylococcus aureus

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering
  • Biotechnology


Dive into the research topics of 'Staphylococcal adhesion to collagen in intpa-articular sepsis'. Together they form a unique fingerprint.

Cite this