Stage-Based Management of Type 2 Diabetes Mellitus with Heart Failure

Patricia Mejia Osuna, Spandana J. Brown, Laila S. Tabatabai, Dale J. Hamilton

Research output: Contribution to journalReview article

Abstract

Type 2 diabetes negatively impacts heart failure outcomes. Insulin resistance, central adiposity, dyslipidemia, and altered cellular substrate metabolism each have a mechanistic role. Management strategies focused solely on glycemic control have had limited success. However, three new classes of drugs, each with several options, offer the promise of improved diabetes management in heart failure. Unlike earlier classes, these medications have had favorable cardiovascular outcomes. In this review, we present a therapeutic guide for metabolic treatment based on the stages of heart failure.

Original languageEnglish (US)
Pages (from-to)257-265
Number of pages9
JournalMethodist DeBakey cardiovascular journal
Volume14
Issue number4
DOIs
StatePublished - Oct 1 2018

Keywords

  • DPP-4 inhibitors
  • GLP-1 agonists
  • heart failure
  • SGLT2 inhibitors
  • therapeutic options
  • type 2 diabetes

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Stage-Based Management of Type 2 Diabetes Mellitus with Heart Failure'. Together they form a unique fingerprint.

  • Cite this