Squamous cell carcinoma with perineural invasion presenting as a Tolosa-Hunt-like syndrome: A potential pitfall in diagnosis

Bita Esmaeli, Lawrence Ginsberg, Helmuth Goepfert, Michael Deavers

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

Purpose: To describe a case of perineural invasion resulting from squamous cell carcinoma of forehead. Methods: Case report. Results: Perineural invasion resulting from squamous cell carcinoma of the periocular skin can present as a Tolosa-Hunt-like syndrome with lack of radiologic findings on magnetic resonance imaging (MRI) in its early stages. Conclusion: A high level of suspicion for perineural invasion is required when assessing multiple cranial nerve palsies in patients with a history of cutaneous malignancy, despite negative sequential MRI. Perineural invasion must be ruled out by a biopsy of the involved nerves, whenever possible, before empiric therapy with systemic steroids is contemplated.

Original languageEnglish (US)
Pages (from-to)450-452
Number of pages3
JournalOphthalmic Plastic and Reconstructive Surgery
Volume16
Issue number6
DOIs
StatePublished - 2000

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology

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