TY - JOUR
T1 - Spreading Pigmented Actinic Keratosis
T2 - An Electron Microscopic Study
AU - Dinehart, Scott M.
AU - Sanchez, Ramon
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Spreading pigmented actinic keratosis is a rarely reported premalignant, pigmented, epidermal tumor that can be difficult to distinguish clinically from other benign and malignant pigmented lesions. In an attempt to determine the cause of clinical hyperpigmentation, seven lesions from five patients were examined by light microscopy. Three of these lesions were also examined using electron microscopy. Findings from these studies indicate that hyperpigmentation is due to enhanced melanosome formation and distribution and not to a melanocytekeratinocyte melanosome transfer block.
AB - Spreading pigmented actinic keratosis is a rarely reported premalignant, pigmented, epidermal tumor that can be difficult to distinguish clinically from other benign and malignant pigmented lesions. In an attempt to determine the cause of clinical hyperpigmentation, seven lesions from five patients were examined by light microscopy. Three of these lesions were also examined using electron microscopy. Findings from these studies indicate that hyperpigmentation is due to enhanced melanosome formation and distribution and not to a melanocytekeratinocyte melanosome transfer block.
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U2 - 10.1001/archderm.1988.01670050024012
DO - 10.1001/archderm.1988.01670050024012
M3 - Article
C2 - 2452605
AN - SCOPUS:0023927248
VL - 124
SP - 680
EP - 683
JO - Archives of Dermatology
JF - Archives of Dermatology
SN - 0003-987X
IS - 5
ER -