Spinal Schwannoma and Meningioma Mimicking a Single Mass at the Craniocervical Junction Subsequent to Remote Radiation Therapy for Acne Vulgaris

Brandon D. Liebelt, Ali S. Haider, William J. Steele, Chandan Krishna, J. Bob Blacklock

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Background Schwannomas and meningiomas are relatively common tumors of the nervous system. They have been reported in the literature as existing concurrently as a single mass, but very rarely have they been shown to present at the craniocervical junction. Case Description We present a rare and interesting case of a patient previously treated with radiation therapy for acne vulgaris and who presented to us with a concurrent schwannoma and meningioma of the craniocervical junction mimicking a single mass. Conclusions These tumors can be solitary or mixed masses, and are known to be associated with certain disease processes such as long-term sequelae of radiation therapy and neurofibromatosis type 2. The precise mechanism behind the formation of these tumors is unknown; however, molecular cues in the tumor microenvironment may play a role.

Original languageEnglish (US)
Pages (from-to)484.e13-484.e16
JournalWorld neurosurgery
Volume93
DOIs
StatePublished - Sep 1 2016

Keywords

  • Meningioma
  • Radiation-induced tumor
  • Schwannoma
  • Skull base tumor

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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