Spectroscopically enhancing electrical nanotraps

Gengfeng Zheng, Lidong Qin, Chad A. Mirkin

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


(Figure Presented) Electrical traps with Raman hot spots: On-wire-lithography (OWL) nanotraps electrically localize DNA in a nanometerscale gap (see picture, red oligonucleotides with Raman dyes), which allows for the identification of the localized material by surface-enhanced Raman spectroscopy. With microfluidic delivery, sample volumes as small as 1 mL with target concentrations as low as 230 fm can be studied without secondary amplification.

Original languageEnglish (US)
Pages (from-to)1938-1941
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number10
StatePublished - Feb 22 2008


  • DNA
  • Electric field
  • Lithography
  • Nanotechnology
  • Surface-enhanced Raman spectroscopy

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Medicine(all)


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