(Figure Presented) Electrical traps with Raman hot spots: On-wire-lithography (OWL) nanotraps electrically localize DNA in a nanometerscale gap (see picture, red oligonucleotides with Raman dyes), which allows for the identification of the localized material by surface-enhanced Raman spectroscopy. With microfluidic delivery, sample volumes as small as 1 mL with target concentrations as low as 230 fm can be studied without secondary amplification.
- Electric field
- Surface-enhanced Raman spectroscopy
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